Dimethyl Sulfoxide → N-[2-(Dimethylamino)-2-phenylethyl]-10-[(2'-methoxy-1,1'-biphenyl-4-YL)carbonyl]-10,11-dihydro-5H-pyrrolo[2,1-C][1,4]benzodiazepine-3-carboxamide
Reaction equation
[CH3:49][S:50]([CH3:51])=[O:52].[CH3:53][CH2:54][N:55]([CH2:56][CH3:57])[CH2:58][CH3:59].[CH3:60][C:61]#[N:62].[Cl:1][C:2]([C:3](=[O:4])[c:5]1[cH:6][cH:7][c:8]2[n:14]1[CH2:13][c:12]1[c:11]([cH:18][cH:17][cH:16][cH:15]1)[N:10]([C:19](=[O:20])[c:21]1[cH:22][cH:23][c:24](-[c:27]3[c:28]([O:33][CH3:34])[cH:29][cH:30][cH:31][cH:32]3)[cH:25][cH:26]1)[CH2:9]2)([Cl:35])[Cl:36].[NH2:37][CH2:38][CH:39]([c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1)[N:46]([CH3:47])[CH3:48]>>[C:3](=[O:4])([c:5]1[cH:6][cH:7][c:8]2[n:14]1[CH2:13][c:12]1[c:11]([cH:18][cH:17][cH:16][cH:15]1)[N:10]([C:19](=[O:20])[c:21]1[cH:22][cH:23][c:24](-[c:27]3[c:28]([O:33][CH3:34])[cH:29][cH:30][cH:31][cH:32]3)[cH:25][cH:26]1)[CH2:9]2)[NH:37][CH2:38][CH:39]([c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1)[N:46]([CH3:47])[CH3:48]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-b6af96690e4e44ba90c90febe6e2c088
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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