Dichloromethane → 3-[(4-Chloro-2,6-difluorophenyl)(cyclopropyl)methyl]-7-[(methylsulfonyl)methyl]-1H-indole
Reaction equation
[CH3:22][S:23](=[O:24])(=[O:25])[CH2:26][c:27]1[cH:28][cH:29][cH:30][c:31]2[cH:32][cH:33][nH:34][c:35]12.[Cl:1][c:2]1[cH:3][c:4]([F:14])[c:5]([CH:9]([OH:10])[CH:11]2[CH2:12][CH2:13]2)[c:6]([F:8])[cH:7]1.[Cl:36][CH2:37][Cl:38].[OH:15][C:16]([C:17]([F:18])([F:19])[F:20])=[O:21]>>[Cl:1][c:2]1[cH:3][c:4]([F:14])[c:5]([CH:9]([CH:11]2[CH2:12][CH2:13]2)[c:32]2[c:31]3[cH:30][cH:29][cH:28][c:27]([CH2:26][S:23]([CH3:22])(=[O:24])=[O:25])[c:35]3[nH:34][cH:33]2)[c:6]([F:8])[cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-b2891e2e30344563a22c8cfec20d4f04
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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