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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 284027Generated: October 30, 2026

Tetrahydrofuran → 6-bromo-2-(4-methanesulfonylbenzyl)-4-phenyl-3-(2,2,2-trifluoro-1-hydroxyethyl)-2H-isoquinolin-1-one

https://huagongshe.com/reaction/284027

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant(Trifluoromethyl)trimethylsilaneHCID 552549—
Reactant6-Bromo-2-(4-methanesulfonylbenzyl)-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carbaldehydeHCID 23060816—
Product6-bromo-2-(4-methanesulfonylbenzyl)-4-phenyl-3-(2,2,2-trifluoro-1-hydroxyethyl)-2H-isoquinolin-1-oneHCID 23060593—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-3e8aec5f46824232acb7d48a37e63641
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)