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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 284141Generated: October 25, 2026

1-Ethyl-4-(prop-2-ynyl)piperazine → N-(4-(2-(3-(4-ethylpiperazin-1-yl)prop-1-ynyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

https://huagongshe.com/reaction/284141

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Ethyl-4-(prop-2-ynyl)piperazineHCID 21190741—
ReactantN-(3-fluoro-4-(2-iodothieno[3,2-b]pyridin-7-yloxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideHCID 67347909—
ProductN-(4-(2-(3-(4-ethylpiperazin-1-yl)prop-1-ynyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideHCID 67348716—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-6f45a60ac573444d8faf502b6129ed8c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)