Tetrahydrofuran → 1,1,1-Trifluoro-3-phenyl-2-(1-phenylindazol-5-yl)propan-2-ol

HRID 284170Notes

Reaction equation

HRID 284170 reaction equation
[Br:23][Mg:24][c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1.[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[c:1]1(-[n:7]2[n:8][cH:9][c:10]3[cH:11][c:12]([C:16]4([C:19]([F:20])([F:21])[F:22])[O:17][CH2:18]4)[cH:13][cH:14][c:15]23)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[n:7]2[n:8][cH:9][c:10]3[cH:11][c:12]([C:16]([OH:17])([CH2:18][c:25]4[cH:26][cH:27][cH:28][cH:29][cH:30]4)[C:19]([F:20])([F:21])[F:22])[cH:13][cH:14][c:15]23)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 579432511-Phenyl-5-[2-(trifluoromethyl)oxiran-2-yl]indazoleHCID 178418255HCID 178418255, compound

Product 1

HCID 579434241,1,1-Trifluoro-3-phenyl-2-(1-phenylindazol-5-yl)propan-2-ol

Sources & evidence

ORD record
ord-b993863aafbc44648fc91be249fadb05
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…