Triethylamine → 4-[6-(2-Chloro-6-fluoro-benzoylamino)-pyridin-2-yloxy]-2-methyl-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH3:22])[CH2:10][CH:11]([O:14][c:15]2[n:16][c:17]([NH2:21])[cH:18][cH:19][cH:20]2)[CH2:12][CH2:13]1.[CH2:41]1[O:42][CH2:43][CH2:44][O:45][CH2:46]1.[CH3:23][CH2:24][N:25]([CH2:26][CH3:27])[CH2:28][CH3:29].[Cl:30][c:31]1[c:32]([C:33](=[O:34])[Cl:35])[c:36]([F:40])[cH:37][cH:38][cH:39]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH3:22])[CH2:10][CH:11]([O:14][c:15]2[n:16][c:17]([NH:21][C:33]([c:32]3[c:31]([Cl:30])[cH:39][cH:38][cH:37][c:36]3[F:40])=[O:34])[cH:18][cH:19][cH:20]2)[CH2:12][CH2:13]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-acd0ad698cab4642ae3ed86dddd24321
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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