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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 284288Generated: October 27, 2026

Tetrahydrofuran → (Z)-N-(5-tert-butyl-3-((1-hydroxycyclohexyl)methyl)thiazol-2(3H)-ylidene)-5-chloro-2-methoxybenzamide

https://huagongshe.com/reaction/284288

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantThionyl ChlorideHCID 24386—
Reactant5-Chloro-o-anisic acidHCID 76970—
Reactant1-((5-tert-butyl-2-iminothiazol-3(2H)-yl)methyl)cyclohexanolHCID 66851825—
Product(Z)-N-(5-tert-butyl-3-((1-hydroxycyclohexyl)methyl)thiazol-2(3H)-ylidene)-5-chloro-2-methoxybenzamideHCID 66851559—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-fb3b9d87a96748d4854f477b4703cece
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)