HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl bromoacetate → HCID 68853462, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl bromoacetate | HCID 79177 | — |
| Reactant | Sodium bis(trimethylsilyl)amide | HCID 2724254 | — |
| Reactant | HCID 21943473 | HCID 21943473 | — |
| Product | HCID 68853462 | HCID 68853462 | 49.3% |
Reaction Steps
According to example 1, 5.07 g (16 mmol) of 3-(4,4-dimethyl-heptanoyl)-4-methyl-5-phenyl-oxazolidin-2-one, 18 mL (1N, 18 mmol) of NaHMDS solution and 4.72 mL (32 mmol) of bromo-acetic acid tert-butyl ester gave 3.40 g (49.3%) of the title compound as a crystalline solid. m.p.: 83-85° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07419981B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-74323a26148845b5be5e96189efc452f |
| Source note | uspto-grants-2008_09 |