huagongshe.com
HRID28437

反应详情

EQUATION

反应方程式

HRID 28437 的结构方程式

REACTANTS

反应物

3
结构：CC(C)(C)OC(=O)CBr
HCID79177

Acetic acid, bromo-, 1,1-dimethylethyl ester

C6H11BrO2

结构：C[Si](C)(C)[N-][Si](C)(C)C.[Na+]
HCID2724254

Sodium bis(trimethylsilyl)amide

C6H18NNaSi2

结构：CCCC(C)(C)CCC(=O)N1C(=O)OC(c2ccccc2)C1C
HCID21943473

未命名化合物

PRODUCTS

生成物

1
结构：CCCC(C)(C)C[C@@H](CC(=O)OC(C)(C)C)C(=O)N1C(=O)O[C@H](c2ccccc2)[C@@H]1C
HCID68853462

未命名化合物

收率 49.3%

PROCEDURE

实验过程

According to example 1, 5.07 g (16 mmol) of 3-(4,4-dimethyl-heptanoyl)-4-methyl-5-phenyl-oxazolidin-2-one, 18 mL (1N, 18 mmol) of NaHMDS solution and 4.72 mL (32 mmol) of bromo-acetic acid tert-butyl ester gave 3.40 g (49.3%) of the title compound as a crystalline solid. m.p.: 83-85° C.