Hydrochloric Acid → HCID 86589983, compound

HRID 28441Notes

Reaction equation

C([O:5][C:6](=[O:17])[CH2:7][CH:8]([NH2:16])[CH2:9][C:10]([CH3:15])([CH3:14])[CH2:11][CH2:12][CH3:13])(C)(C)C.[ClH:18]>>[ClH:18].[NH2:16][C@@H:8]([CH2:9][C:10]([CH3:14])([CH3:15])[CH2:11][CH2:12][CH3:13])[CH2:7][C:6]([OH:17])=[O:5]

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 85871156HCID 85871156, compound

Product 1

HCID 86589983HCID 86589983, compound

Procedure

According to example 1, 3-amino-5,5-dimethyl-octanoic acid tert-butyl ester was treated with 3N HCl to provide 286 mg of the title compound as a solid. MS (APCl), m/z: 188.1 (M+1)+. 186.1 (M−1)+. Anal. Calc'd for C10H21NO2.HCl.0.12H2O: C: 53.17; H, 9.92; N, 6.20; Cl: 15.69; Found: C: 53.19; H, 10.00; N, 6.08; Cl: 15.25. α=+20° (MeOH). MP: 194.2-195.2° C.

Sources & evidence

ORD record: ord-8cfb2e6b55e0417c9be3cf8de096bd65
Source dataset: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07419981B2

Reaction notes

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