Hydrochloric Acid → 1-(4-methoxyphenyl)-2,2-dimethyl-N-(6-(4-(N-methylsulfamoyl)-phenyl)pyridin-2-yl)cyclo-propanecarboxamide

HRID 284458Notes

Reaction equation

HRID 284458 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([C:9]2([C:14](=[O:15])[Cl:16])[C:10]([CH3:12])([CH3:13])[CH2:11]2)[cH:7][cH:8]1.[ClH:35].[NH2:17][c:18]1[cH:19][cH:20][cH:21][c:22](-[c:24]2[cH:25][cH:26][c:27]([S:30](=[O:31])(=[O:32])[NH:33][CH3:34])[cH:28][cH:29]2)[n:23]1.[cH:36]1[cH:37][cH:38][n:39][cH:40][cH:41]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([C:9]2([C:14](=[O:15])[NH:17][c:18]3[cH:19][cH:20][cH:21][c:22](-[c:24]4[cH:25][cH:26][c:27]([S:30](=[O:31])(=[O:32])[NH:33][CH3:34])[cH:28][cH:29]4)[n:23]3)[C:10]([CH3:12])([CH3:13])[CH2:11]2)[cH:7][cH:8]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 1049PyridineHCID 591658661-(4-Methoxyphenyl)-2,2-dimethylcyclopropanecarbonyl chlorideHCID 591658894-(6-aminopyridin-2-yl)-N-methylbenzenesulfonamide

Product 1

HCID 591661601-(4-methoxyphenyl)-2,2-dimethyl-N-(6-(4-(N-methylsulfamoyl)-phenyl)pyridin-2-yl)cyclo-propanecarboxamide

Sources & evidence

ORD record
ord-cb199666a6ba41e0b0c199e53a29c2a1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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