Sodium ion → 4-[2-(2,2-Dimethyl-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)-1,3-thiazol-4-yl]benzonitrile

HRID 284728Notes

Reaction equation

HRID 284728 reaction equation
[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6](-[c:9]2[n:10][c:11]([NH:14][C:15]([CH:16]=[CH:17][C:18](=[O:19])[O:20][CH3:21])([CH3:22])[CH3:23])[s:12][cH:13]2)[cH:7][cH:8]1.[CH3:24][O-:25].[Na+:26].[O:27]1[CH2:28][CH2:29][CH2:30][CH2:31]1>>[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6](-[c:9]2[n:10][c:11]([N:14]3[C:15]([CH3:22])([CH3:23])[CH:16]=[CH:17][C:18]3=[O:19])[s:12][cH:13]2)[cH:7][cH:8]1

Participants

5

Reactant 4

HCID 923Sodium ionHCID 8028TetrahydrofuranHCID 3826051MethoxideHCID 91041159Methyl 4-[[4-(4-cyanophenyl)-1,3-thiazol-2-yl]amino]-4-methylpent-2-enoate

Product 1

HCID 247386264-[2-(2,2-Dimethyl-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)-1,3-thiazol-4-yl]benzonitrile

Sources & evidence

ORD record
ord-0bc28d6a805841cebc59c84e6dbbf140
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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