Hydrochloric Acid → 7-Bromo-2-(2-(tert-butyl(3-(3-(thiazol-5-yl)prop-2-ynyloxy)propyl)amino)-2-oxoacetyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid
Reaction equation
[Br:1][c:2]1[c:3]([O:38][CH3:39])[cH:4][c:5]2[c:10]([cH:11]1)[CH:9]([C:12](=[O:13])[O:14][CH2:15][CH3:16])[N:8]([C:17]([C:18](=[O:19])[N:20]([CH2:21][CH2:22][CH2:23][O:24][CH2:25][C:26]#[C:27][c:28]1[cH:29][n:30][cH:31][s:32]1)[C:33]([CH3:34])([CH3:35])[CH3:36])=[O:37])[CH2:7][CH2:6]2.[ClH:49].[K+:41].[O:42]1[CH2:43][CH2:44][O:45][CH2:46][CH2:47]1.[OH-:40].[OH2:48]>>[Br:1][c:2]1[c:3]([O:38][CH3:39])[cH:4][c:5]2[c:10]([cH:11]1)[CH:9]([C:12](=[O:13])[OH:14])[N:8]([C:17]([C:18](=[O:19])[N:20]([CH2:21][CH2:22][CH2:23][O:24][CH2:25][C:26]#[C:27][c:28]1[cH:29][n:30][cH:31][s:32]1)[C:33]([CH3:34])([CH3:35])[CH3:36])=[O:37])[CH2:7][CH2:6]2Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-5b3986d688044225ad00ce70aa896905
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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