Potassium Cation → 3-Fluoro-4-(4-nitrophenyl)pyridine

HRID 285011Notes

Reaction equation

HRID 285011 reaction equation
[C:21](=[O:22])([O-:23])[O-:24].[CH3:27][O:28][CH2:29][CH2:30][O:31][CH3:32].[Cl:13][c:14]1[c:15]([F:20])[cH:16][n:17][cH:18][cH:19]1.[K+:25].[K+:26].[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][cH:6][c:7]([B:10]([OH:11])[OH:12])[cH:8][cH:9]1.[Pd:33].[c:34]1([P:35]([c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)[c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[cH:48][cH:49][cH:50][cH:51][cH:52]1.[c:53]1([P:54]([c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)[c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)[cH:67][cH:68][cH:69][cH:70][cH:71]1.[c:72]1([P:73]([c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)[c:80]2[cH:81][cH:82][cH:83][cH:84][cH:85]2)[cH:86][cH:87][cH:88][cH:89][cH:90]1.[c:91]1([P:92]([c:93]2[cH:94][cH:95][cH:96][cH:97][cH:98]2)[c:99]2[cH:100][cH:101][cH:102][cH:103][cH:104]2)[cH:105][cH:106][cH:107][cH:108][cH:109]1>>[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][cH:6][c:7](-[c:14]2[c:15]([F:20])[cH:16][n:17][cH:18][cH:19]2)[cH:8][cH:9]1

Participants

8

Reactant 7

HCID 813Potassium Cation2×HCID 80711,2-DimethoxyethaneHCID 11776Triphenylphosphine4×HCID 19660Carbonate IonHCID 23938PalladiumHCID 27735524-Nitrophenylboronic acidHCID 38524294-Chloro-3-fluoropyridine

Product 1

HCID 690819133-Fluoro-4-(4-nitrophenyl)pyridine

Sources & evidence

ORD record
ord-ba36d77f5f094d7d88c2bc883d227ba4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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