Tetrahydrofuran → Ethyl (5-chloro-1,3-dihydro-2-benzofuran-1-yl)acetate

HRID 285193Notes

Reaction equation

HRID 285193 reaction equation
[C:26](=[O:27])([O-:28])[O-:29].[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:12][CH2:13][O:14][C:15](=[O:16])[CH2:17][P:18]([O:19][CH2:20][CH3:21])([O:22][CH2:23][CH3:24])=[O:25].[Cl:1][c:2]1[cH:3][c:4]2[c:5]([cH:10][cH:11]1)[CH:6]([OH:9])[O:7][CH2:8]2.[Cs+:30].[Cs+:31]>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([cH:10][cH:11]1)[CH:6]([CH2:17][C:15]([O:14][CH2:13][CH3:12])=[O:16])[O:7][CH2:8]2

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 13345Triethyl phosphonoacetateHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 693101565-Chloro-1,3-dihydroisobenzofuran-1-ol

Product 1

HCID 86592978Ethyl (5-chloro-1,3-dihydro-2-benzofuran-1-yl)acetate

Sources & evidence

ORD record
ord-b65b2de9099a4f22bdc905035e6ef050
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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