1,2-Dichloroethane → 3,4,5,6-tetrahydro-2,3,10-triaza-benzo[e]azulene-1-carboxylic acid [1-(3-azetidin-1-yl-propyl)-1H-pyrazol-3-yl]-amide

HRID 285228Notes

Reaction equation

HRID 285228 reaction equation
[Cl:31][CH2:32][CH2:33][Cl:34].[Cl:35][CH2:36][Cl:37].[N:18]1([CH2:22][CH2:23][CH2:24][n:25]2[n:26][c:27]([NH2:30])[cH:28][cH:29]2)[CH2:19][CH2:20][CH2:21]1.[c:1]1([C:15](=[O:16])[OH:17])[n:2][nH:3][c:4]2[c:10]1-[c:9]1[c:8]([cH:14][cH:13][cH:12][n:11]1)[CH2:7][CH2:6][CH2:5]2>>[c:1]1([C:15](=[O:17])[NH:30][c:27]2[n:26][n:25]([CH2:24][CH2:23][CH2:22][N:18]3[CH2:19][CH2:20][CH2:21]3)[cH:29][cH:28]2)[n:2][nH:3][c:4]2[c:10]1-[c:9]1[c:8]([cH:14][cH:13][cH:12][n:11]1)[CH2:7][CH2:6][CH2:5]2

Participants

5

Reactant 4

HCID 111,2-DichloroethaneHCID 6344DichloromethaneHCID 121330693,4,5,6-Tetrahydro-2,3,10-triaza-benzo[e]azulene-1-carboxylic acidHCID 121330701-(3-azetidin-1-yl-propyl)-1H-pyrazol-3-ylamine

Product 1

HCID 101506503,4,5,6-tetrahydro-2,3,10-triaza-benzo[e]azulene-1-carboxylic acid [1-(3-azetidin-1-yl-propyl)-1H-pyrazol-3-yl]-amide

Sources & evidence

ORD record
ord-f77cb306f3ae411b8e6bedfe54637636
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…