Trifluoroacetic acid → 5-Cyclobutyl-1,3-thiazol-2-amine

HRID 285304Notes

Reaction equation

HRID 285304 reaction equation
[NH2:1][c:2]1[s:3][c:4]([C:7]2([OH:11])[CH2:8][CH2:9][CH2:10]2)[cH:5][n:6]1.[OH:12][C:13]([C:14]([F:15])([F:16])[F:17])=[O:18]>>[NH2:1][c:2]1[s:3][c:4]([CH:7]2[CH2:8][CH2:9][CH2:10]2)[cH:5][n:6]1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 227313761-(2-Amino-1,3-thiazol-5-yl)cyclobutan-1-ol

Product 1

HCID 129914235-Cyclobutyl-1,3-thiazol-2-amine

Sources & evidence

ORD record
ord-c5933edc92a94cc5995f864acd3e1b72
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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