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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 285315Generated: October 30, 2026

Tetrahydrofuran → N-{4-[6-Cyano-7-(2-hydroxy-3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy]-2-fluorophenyl)-N'-(thiazol-2-yl)urea

https://huagongshe.com/reaction/285315

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantPyrrolidineHCID 31268—
ReactantN-[4-(6-Cyano-7-oxiranylmethoxyquinolin-4-yloxy)-2-fluorophenyl]-N'-(thiazol-2-yl)ureaHCID 22936623—
ProductN-{4-[6-Cyano-7-(2-hydroxy-3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy]-2-fluorophenyl)-N'-(thiazol-2-yl)ureaHCID 86591470—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-0ffcde62bfa3408caa5eb9a52d17c8ba
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)