Dimethylformamide → 3-(3-Chloro-2-fluorophenyl)-1-methylpyrrolidin-3-ol
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][C:10]([OH:13])([c:14]2[c:15]([F:21])[c:16]([Cl:20])[cH:17][cH:18][cH:19]2)[CH2:11][CH2:12]1.[CH2:24]1[NH:25][CH2:26][CH2:27][O:28][CH2:29]1.[CH:30]([N:31]([CH3:32])[CH3:33])=[O:34].[I:22][CH3:23]>>[CH3:1][N:8]1[CH2:9][C:10]([OH:13])([c:14]2[c:15]([F:21])[c:16]([Cl:20])[cH:17][cH:18][cH:19]2)[CH2:11][CH2:12]1Participants
5
Sources & evidence
- ORD record
- ord-0121f1382c4d4619be4dd00f39a101d8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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