3-(Trifluoromethyl)benzylamine → Urea, N-5-isoquinolinyl-N'-[[3-(trifluoromethyl)phenyl]methyl]-
Reaction equation
[CH2:30]1[CH2:31][CH2:32][C:33]2=[N:38][CH2:37][CH2:36][CH2:35][N:34]2[CH2:39][CH2:40]1.[Cl:13][C:14]([C:15](=[O:16])[NH:17][c:18]1[c:19]2[cH:20][cH:21][n:22][cH:23][c:24]2[cH:25][cH:26][cH:27]1)([Cl:28])[Cl:29].[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][NH2:7])[cH:8][cH:9][cH:10]1)([F:11])[F:12]>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][NH:7][C:15](=[O:16])[NH:17][c:18]2[c:19]3[cH:20][cH:21][n:22][cH:23][c:24]3[cH:25][cH:26][cH:27]2)[cH:8][cH:9][cH:10]1)([F:11])[F:12]Participants
4
Sources & evidence
- ORD record
- ord-0ca638b66f9d4bb39013ff6ba7ab7417
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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