Hydrochloric Acid → 1-[4-(2-Chloro-7-methyl-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-piperazin-1-yl]-2-hydroxy-propan-1-one

HRID 285867Notes

Reaction equation

HRID 285867 reaction equation
[CH3:26][CH:27]([OH:28])[C:29]([OH:30])=[O:31].[Cl:2][c:3]1[n:4][c:5]([N:20]2[CH2:21][CH2:22][O:23][CH2:24][CH2:25]2)[c:6]2[c:7]([n:8]1)[c:9]([CH3:19])[c:10]([CH2:12][N:13]1[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]1)[s:11]2.[ClH:1]>>[Cl:2][c:3]1[n:4][c:5]([N:20]2[CH2:21][CH2:22][O:23][CH2:24][CH2:25]2)[c:6]2[c:7]([n:8]1)[c:9]([CH3:19])[c:10]([CH2:12][N:13]1[CH2:14][CH2:15][N:16]([C:29]([CH:27]([CH3:26])[OH:28])=[O:30])[CH2:17][CH2:18]1)[s:11]2

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 612Lactic AcidHCID 866235192-Chloro-7-methyl-4-morpholino-6-((piperazin-1-yl)methyl)thieno[3,2-d]pyrimidine

Product 1

HCID 866235481-[4-(2-Chloro-7-methyl-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-piperazin-1-yl]-2-hydroxy-propan-1-one

Sources & evidence

ORD record
ord-e9b07101fad0464cbe6f34bff9de1fc4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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