Acetone → 1-[cis-4-(tert-Butyl-dimethyl-silanyloxy)-cyclohexyl]-3-(2,6-dichloro-4-isopropoxy-benzyl)-pyrrolidin-2-one
Reaction equation
[Br:31][CH:32]([CH3:33])[CH3:34].[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH:7]1[CH2:8][CH2:9][CH:10]([N:13]2[C:14](=[O:28])[CH:15]([CH2:18][c:19]3[c:20]([Cl:27])[cH:21][c:22]([OH:26])[cH:23][c:24]3[Cl:25])[CH2:16][CH2:17]2)[CH2:11][CH2:12]1)([CH3:29])[CH3:30].[C:35](=[O:36])([O-:37])[O-:38].[CH3:41][C:42](=[O:43])[CH3:44].[K+:39].[K+:40]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH:7]1[CH2:8][CH2:9][CH:10]([N:13]2[C:14](=[O:28])[CH:15]([CH2:18][c:19]3[c:20]([Cl:27])[cH:21][c:22]([O:26][CH:32]([CH3:33])[CH3:34])[cH:23][c:24]3[Cl:25])[CH2:16][CH2:17]2)[CH2:11][CH2:12]1)([CH3:29])[CH3:30]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-bda54382f50149c0b621e36a4d424795
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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