反应详情

Following the method described in Example 26, 4-(5-bromo-2-methyl-phenyl)-6-chloro-pyrimidin-2-ylamine and 4-oxazol-4-yl-phenylamine provided the title compound (61% yield). 1H NMR (CD3OD) δ 2.41 (s, 3H, CH3), 6.37 (s, 1H, Ar), 7.38 (d, 1H, J=7.8 Hz, Ar), 7.61 (s, 1H, Ar), 7.66-7.69 (m, 2H, Ar), 7.81 (d, 2H, J=8.7 Hz, Ar), 7.99 (d, 2H, J=8.5 Hz, Ar), 8.43 (br s, 1H, NH).