HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Oxazol-4-yl)aniline → HCID 131727011, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Oxazol-4-yl)aniline | HCID 22397853 | — |
| Reactant | 2-Amino-4-chloro-6-(2-methyl-5-bromo-phenyl)-pyrimidine | HCID 86004341 | — |
| Product | HCID 131727011 | HCID 131727011 | 61% |
Reaction Steps
Following the method described in Example 26, 4-(5-bromo-2-methyl-phenyl)-6-chloro-pyrimidin-2-ylamine and 4-oxazol-4-yl-phenylamine provided the title compound (61% yield). 1H NMR (CD3OD) δ 2.41 (s, 3H, CH3), 6.37 (s, 1H, Ar), 7.38 (d, 1H, J=7.8 Hz, Ar), 7.61 (s, 1H, Ar), 7.66-7.69 (m, 2H, Ar), 7.81 (d, 2H, J=8.7 Hz, Ar), 7.99 (d, 2H, J=8.5 Hz, Ar), 8.43 (br s, 1H, NH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07419984B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-0b71b2605380497bb8919673a4a508af |
| Source note | uspto-grants-2008_09 |