Dichloromethane → (+/-)-3,4-bis-cyclopropylmethoxy-N-[(3RS,4RS)-4-(3,4-dimethoxyphenyl)-7-oxabicyclo[4.1.0]-hept-3-yl]benzamide

HRID 286109Notes

Reaction equation

HRID 286109 reaction equation
[CH:1]1([CH2:4][O:5][c:6]2[cH:7][c:8]([C:9](=[O:10])[NH:11][CH:12]3[CH2:13][CH:14]=[CH:15][CH2:16][CH:17]3[c:18]3[cH:19][c:20]([O:26][CH3:27])[c:21]([O:24][CH3:25])[cH:22][cH:23]3)[cH:28][cH:29][c:30]2[O:31][CH2:32][CH:33]2[CH2:34][CH2:35]2)[CH2:2][CH2:3]1.[Cl:36][c:37]1[cH:38][cH:39][cH:40][c:41]([C:42]([O:43][OH:45])=[O:44])[cH:46]1.[Cl:47][CH2:48][Cl:49]>>[CH:1]1([CH2:4][O:5][c:6]2[cH:7][c:8]([C:9](=[O:10])[NH:11][CH:12]3[CH2:13][CH:14]4[CH:15]([CH2:16][CH:17]3[c:18]3[cH:19][c:20]([O:26][CH3:27])[c:21]([O:24][CH3:25])[cH:22][cH:23]3)[O:44]4)[cH:28][cH:29][c:30]2[O:31][CH2:32][CH:33]2[CH2:34][CH2:35]2)[CH2:2][CH2:3]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 70297m-Chloroperbenzoic acidHCID 689862583,4-bis(cyclopropylmethoxy)-N-[6-(3,4-dimethoxyphenyl)cyclohex-3-en-1-yl]benzamide

Product 1

HCID 86601279(+/-)-3,4-bis-cyclopropylmethoxy-N-[(3RS,4RS)-4-(3,4-dimethoxyphenyl)-7-oxabicyclo[4.1.0]-hept-3-yl]benzamide

Sources & evidence

ORD record
ord-d8177440fb2b4e10b859f9266a2a3f29
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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