Potassium Cation → 2,3-Dihydro-2,4,6,7-tetramethyl-2-[(1,2,3,4-tetrahydroisoquinolin-2-yl)methyl]-5-benzofuranamine

HRID 286116Notes

Reaction equation

HRID 286116 reaction equation
[Br:1][CH2:2][C:3]1([CH3:16])[O:4][c:5]2[c:6]([c:8]([CH3:15])[c:9]([NH2:14])[c:10]([CH3:13])[c:11]2[CH3:12])[CH2:7]1.[C:27](=[O:28])([O-:29])[O-:30].[CH2:17]1[NH:18][CH2:19][CH2:20][c:21]2[cH:22][cH:23][cH:24][cH:25][c:26]21.[CH3:33][N:34]([CH3:35])[C:36](=[O:37])[CH3:38].[K+:31].[K+:32].[OH2:39]>>[CH2:2]([C:3]1([CH3:16])[O:4][c:5]2[c:6]([c:8]([CH3:15])[c:9]([NH2:14])[c:10]([CH3:13])[c:11]2[CH3:12])[CH2:7]1)[N:18]1[CH2:17][c:26]2[c:21]([cH:22][cH:23][cH:24][cH:25]2)[CH2:20][CH2:19]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 70461,2,3,4-TetrahydroisoquinolineHCID 19660Carbonate IonHCID 31374DimethylacetamideHCID 108505902-Bromomethyl-2,3-dihydro-2,4,6,7-tetramethyl-5-benzofuranamine

Product 1

HCID 221110212,3-Dihydro-2,4,6,7-tetramethyl-2-[(1,2,3,4-tetrahydroisoquinolin-2-yl)methyl]-5-benzofuranamine

Sources & evidence

ORD record
ord-75bcc127259d4923bbd6af254cad7d91
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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