Bicarbonate Ion → 4-[4-(4-Trifluoromethoxybenzyl)piperazin-1-yl]phenol

HRID 286375Notes

Reaction equation

HRID 286375 reaction equation
[C:27]([BH3-:28])#[N:29].[CH2:38]([Cl:39])[Cl:40].[CH3:36][OH:37].[F:14][C:15]([O:16][c:17]1[cH:18][cH:19][c:20]([CH:21]=[O:22])[cH:23][cH:24]1)([F:25])[F:26].[Na+:30].[Na+:31].[OH:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]2)[cH:6][cH:7]1.[OH:32][C:33](=[O:34])[O-:35]>>[OH:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([CH2:21][c:20]3[cH:19][cH:18][c:17]([O:16][C:15]([F:14])([F:25])[F:26])[cH:24][cH:23]3)[CH2:12][CH2:13]2)[cH:6][cH:7]1

Participants

8

Reactant 7

HCID 769Bicarbonate IonHCID 887MethanolHCID 923Sodium ion2×HCID 6344DichloromethaneHCID 69573p-(Trifluoromethoxy)benzaldehydeHCID 92467p-(1-Piperazinyl)phenolHCID 498716Cyano-borohydride

Product 1

HCID 307469694-[4-(4-Trifluoromethoxybenzyl)piperazin-1-yl]phenol

Sources & evidence

ORD record
ord-7cd29671abe74604877ddf3830737820
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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