Dimethylformamide → tert-butyl 4-((2-(2-ethyl-1H-benzo[d]imidazol-1-yl)-9-methyl-6-morpholino-9H-purin-8-yl)(hydroxy)methyl)piperidine-1-carboxylate
Reaction equation
[C:44](=[O:45])([O-:46])[O-:47].[CH2:33]([CH3:34])[c:35]1[nH:36][c:37]2[c:38]([n:39]1)[cH:40][cH:41][cH:42][cH:43]2.[Cl:1][c:2]1[n:3][c:4]([N:27]2[CH2:28][CH2:29][O:30][CH2:31][CH2:32]2)[c:5]2[n:6][c:7]([CH:12]([CH:13]3[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]3)[OH:26])[n:8]([CH3:11])[c:9]2[n:10]1.[Cs+:48].[Cs+:49].[O:50]=[CH:51][N:52]([CH3:53])[CH3:54].[O:57]=[C:58]([CH:59]=[CH:60][c:61]1[cH:62][cH:63][cH:64][cH:65][cH:66]1)[CH:67]=[CH:68][c:69]1[cH:70][cH:71][cH:72][cH:73][cH:74]1.[O:75]=[C:76]([CH:77]=[CH:78][c:79]1[cH:80][cH:81][cH:82][cH:83][cH:84]1)[CH:85]=[CH:86][c:87]1[cH:88][cH:89][cH:90][cH:91][cH:92]1.[O:93]=[C:94]([CH:95]=[CH:96][c:97]1[cH:98][cH:99][cH:100][cH:101][cH:102]1)[CH:103]=[CH:104][c:105]1[cH:106][cH:107][cH:108][cH:109][cH:110]1.[Pd:55].[Pd:56]>>[c:2]1(-[n:36]2[c:35]([CH2:33][CH3:34])[n:39][c:38]3[c:37]2[cH:43][cH:42][cH:41][cH:40]3)[n:3][c:4]([N:27]2[CH2:28][CH2:29][O:30][CH2:31][CH2:32]2)[c:5]2[n:6][c:7]([CH:12]([CH:13]3[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]3)[OH:26])[n:8]([CH3:11])[c:9]2[n:10]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-c9c1bb7afd6c49e28a1f9a2f5c3a4272
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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