Acetonitrile → Ethyl 2-chloro-4-(3-fluoro-4-(thiazol-4-yl)phenylamino)pyrimidine-5-carboxylate
Reaction equation
[CH3:36][C:37]#[N:38].[CH:27]([N:28]([CH2:29][CH3:30])[CH:31]([CH3:32])[CH3:33])([CH3:34])[CH3:35].[Cl:1][c:2]1[n:3][cH:4][c:5]([C:9](=[O:10])[O:11][CH2:12][CH3:13])[c:6]([Cl:8])[n:7]1.[F:14][c:15]1[cH:16][c:17]([NH2:26])[cH:18][cH:19][c:20]1-[c:21]1[n:22][cH:23][s:24][cH:25]1>>[Cl:1][c:2]1[n:3][cH:4][c:5]([C:9](=[O:10])[O:11][CH2:12][CH3:13])[c:6]([NH:26][c:17]2[cH:16][c:15]([F:14])[c:20](-[c:21]3[n:22][cH:23][s:24][cH:25]3)[cH:19][cH:18]2)[n:7]1Participants
5
Sources & evidence
- ORD record
- ord-1df534287ce64f5abab2e84664a87cc0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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