Water → 6-({3-(Aminocarbonyl)-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-thienyl}amino)-N-(oxetan-2-ylmethyl)pyridine-2-carboxamide
Reaction equation
[NH2:1][C:2](=[O:3])[c:4]1[c:5]([NH:20][c:21]2[cH:22][cH:23][cH:24][c:25]([C:27](=[O:28])[OH:29])[n:26]2)[s:6][c:7](-[c:9]2[c:10]([F:19])[cH:11][c:12]([C:15]([CH3:16])([CH3:17])[OH:18])[cH:13][cH:14]2)[cH:8]1.[O:30]1[CH:31]([CH2:34][NH2:35])[CH2:32][CH2:33]1.[O:47]=[CH:48][N:49]([CH3:50])[CH3:51].[OH2:36].[OH:37][n:38]1[c:39]2[cH:40][cH:41][cH:42][cH:43][c:44]2[n:45][n:46]1>>[NH2:1][C:2](=[O:3])[c:4]1[c:5]([NH:20][c:21]2[cH:22][cH:23][cH:24][c:25]([C:27](=[O:29])[NH:35][CH2:34][CH:31]3[O:30][CH2:33][CH2:32]3)[n:26]2)[s:6][c:7](-[c:9]2[c:10]([F:19])[cH:11][c:12]([C:15]([CH3:16])([CH3:17])[OH:18])[cH:13][cH:14]2)[cH:8]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-f7d93bd5b12440b2aad4dae8618a031a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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