Hydrochloric Acid → HCID 68852171, compound

HRID 28805Notes

Reaction equation

[N:1]1([CH:7]2[CH2:12][CH2:11][N:10]([C:13](=O)[CH:14]([C:23]3([OH:29])[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]3)[C:15]3[CH:20]=[CH:19][C:18]([Cl:21])=[C:17]([Cl:22])[CH:16]=3)[CH2:9][CH2:8]2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[ClH:31]>>[ClH:21].[ClH:31].[N:1]1([CH:7]2[CH2:12][CH2:11][N:10]([CH2:13][CH:14]([C:23]3([OH:29])[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]3)[C:15]3[CH:20]=[CH:19][C:18]([Cl:21])=[C:17]([Cl:22])[CH:16]=3)[CH2:9][CH2:8]2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 68853046HCID 68853046, compound

Product 1

HCID 68852171HCID 68852171, compound

Procedure

In an analogous manner to Example 1, step 2 1-[2-(1-(4′-bipiperidin-1′-yl)-1-(3,4-dichlorophenyl)ethyl]cyclohexanol dihydrochloride was prepared from 1-[2-(1,4′-bipiperidin-1′-yl)-1-(3,4-dichlorophenyl)-2-oxoethyl]cyclohexanol. MS m/z 439/441/443 ([M+H]+); HRMS: calcd for C24H36Cl2N2O.2.00 HCl, 510.1738; found (ESI), 439.2267.

Sources & evidence

ORD record: ord-ac622bd99d334f0fbd5f1064bf5b599b
Source dataset: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07419980B2

Reaction notes

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