Hydrochloric Acid → Methyl [1-(5-nitropyridin-2-yl)piperidin-4-yl]acetate

HRID 288086Notes

Reaction equation

HRID 288086 reaction equation
[C:23]([N:24]=[P:25]1([N:26]([CH2:27][CH3:28])[CH2:29][CH3:30])[N:31]([CH3:32])[CH2:33][CH2:34][CH2:35][N:36]1[CH3:37])([CH3:38])([CH3:39])[CH3:40].[Cl:1][c:2]1[n:3][cH:4][c:5]([N+:8](=[O:9])[O-:10])[cH:6][cH:7]1.[ClH:11].[NH:12]1[CH2:13][CH2:14][CH:15]([CH2:18][C:19](=[O:20])[O:21][CH3:22])[CH2:16][CH2:17]1>>[c:2]1([N:12]2[CH2:13][CH2:14][CH:15]([CH2:18][C:19](=[O:20])[O:21][CH3:22])[CH2:16][CH2:17]2)[n:3][cH:4][c:5]([N+:8](=[O:9])[O-:10])[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 783082-Chloro-5-nitropyridineHCID 1515259Methyl 4-piperidineacetateHCID 35138512-((1,1-Dimethylethyl)imino)-N,N-diethylhexahydro-1,3-dimethyl-2lambda5-1,3,2-diazaphosphorin-2-amine

Product 1

HCID 47357980Methyl [1-(5-nitropyridin-2-yl)piperidin-4-yl]acetate

Sources & evidence

ORD record
ord-2ccd7d439ccb45338851a354898797e6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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