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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 288092Generated: October 30, 2026

Dimethylformamide → N-[4-(4-amino-6-cyano-7-formylpyrrolo[2,1-f][1,2,4]triazin-5-yl)phenyl]-N'-[2-fluoro-5-(trifluoromethyl)phenyl]urea

https://huagongshe.com/reaction/288092

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTetrahydrofuranHCID 8028—
ReactantHCID 66641333HCID 66641333—
ReactantButyllithiumHCID 178418339—
ProductN-[4-(4-amino-6-cyano-7-formylpyrrolo[2,1-f][1,2,4]triazin-5-yl)phenyl]-N'-[2-fluoro-5-(trifluoromethyl)phenyl]ureaHCID 86635784—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-8590cbcf9d124d79b88aac1089853250
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)