Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 28810Generated: October 29, 2026

N-benzyl-2-(1-hydroxycyclohexyl)-2-(2-naphthyl)acetamide → 1-[2-(benzylamino)-1-(2-naphthyl)ethyl]cyclohexanol Hydrochloride

https://huagongshe.com/reaction/28810

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-benzyl-2-(1-hydroxycyclohexyl)-2-(2-naphthyl)acetamideHCID 68853191—
ReactantHCID 86600404HCID 86600404—
Product1-[2-(benzylamino)-1-(2-naphthyl)ethyl]cyclohexanol HydrochlorideHCID 11509464—

Reaction Steps

In an analogous manner to Example 1, step 2 1-[2-(benzylamino)[1-(2-naphthyl)ethyl]cyclohexanol hydrochloride was prepared from N-benzyl-2-(1-hydroxycyclohexyl)-2-(2-naphthyl)acetamide. HRMS: calcd for C25H29NO.HCl, 395.2016; found (ESI_FT), 360.23164.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07419980B2
Source datasetuspto-grants-2008_09
ORD IDord-1b1252f1fab34fc098416b51746d87ab
Source noteuspto-grants-2008_09