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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 288238Generated: October 25, 2026

Tetrahydrofuran → N-{3-isobutyl-4-[2,2,2-trifluoro-1-(trifluoromethyl)ethyl]phenyl}-3-trifluoromethylpyrazine-2-carboxamide

https://huagongshe.com/reaction/288238

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantEthyl AcetateHCID 8857—
ReactantIodide IonHCID 30165—
Reactant2-Chloro-1-methylpyridiniumHCID 167070—
Reactant3-(Trifluoromethyl)pyrazine-2-carboxylic acidHCID 53630860—
Reactant3-Isobutyl-4-[2,2,2-trifluoro-1-(trifluoromethyl)ethyl]anilineHCID 86619004—
ProductN-{3-isobutyl-4-[2,2,2-trifluoro-1-(trifluoromethyl)ethyl]phenyl}-3-trifluoromethylpyrazine-2-carboxamideHCID 86619011—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-ac4f0b6cc7f74d77b46b1390e61fd965
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)