Tetrahydrofuran → N-{3-isobutyl-4-[2,2,2-trifluoro-1-(trifluoromethyl)ethyl]phenyl}-3-trifluoromethylpyrazine-2-carboxamide
Reaction equation
[CH2:14]([CH:15]([CH3:16])[CH3:17])[c:18]1[cH:19][c:20]([NH2:21])[cH:22][cH:23][c:24]1[CH:25]([C:26]([F:27])([F:28])[F:29])[C:30]([F:31])([F:32])[F:33].[CH2:50]1[O:51][CH2:52][CH2:53][CH2:54]1.[CH3:43][CH2:44][N:45]([CH2:46][CH3:47])[CH2:48][CH3:49].[CH3:55][CH2:56][O:57][C:58](=[O:59])[CH3:60].[Cl:35][c:36]1[cH:37][cH:38][cH:39][cH:40][n+:41]1[CH3:42].[F:1][C:2]([c:3]1[c:4]([C:9](=[O:10])[OH:11])[n:5][cH:6][cH:7][n:8]1)([F:12])[F:13].[I-:34]>>[F:1][C:2]([c:3]1[c:4]([C:9](=[O:11])[NH:21][c:20]2[cH:19][c:18]([CH2:14][CH:15]([CH3:16])[CH3:17])[c:24]([CH:25]([C:26]([F:27])([F:28])[F:29])[C:30]([F:31])([F:32])[F:33])[cH:23][cH:22]2)[n:5][cH:6][cH:7][n:8]1)([F:12])[F:13]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-ac4f0b6cc7f74d77b46b1390e61fd965
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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