HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-{2-[(3S)-3-(methylamino)pyrrolidin-1-yl]-1-[3-(trifluoromethyl)phenyl]ethyl}cyclohexanol dihydrochloride → HCID 86599040, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-{2-[(3S)-3-(methylamino)pyrrolidin-1-yl]-1-[3-(trifluoromethyl)phenyl]ethyl}cyclohexanol dihydrochloride | HCID 68865676 | — |
| Reactant | HCID 86599042 | HCID 86599042 | — |
| Product | HCID 86599040 | HCID 86599040 | — |
Reaction Steps
In an analogous manner to Example 13, step 2, 1-{2-[(3S)-3-(methylamino)pyrrolidin-1-yl]-1-[3-(trifluoromethyl)phenyl]ethyl}cyclohexanol dihydrochloride was prepared from tert-butyl ((3S)-1-{(1-hydroxycyclohexyl)[3-(trifluoromethyl)phenyl]acetyl}pyrrolidin-3-yl)carbamate MS (ESI) m/z 371; HRMS: calcd for C20H29F3N2O+H, 371.23102; found (ESI, [M+H]+), 371.2293.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07419980B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-0757e3ac9c924a088b89e41a6d9ea277 |
| Source note | uspto-grants-2008_09 |