Tetrahydrofuran → 1-[(3-Phenyl-3-cyclohexenyl)methyl]-4-phenyl-1,2,3,6-tetrahydropyridine

HRID 288401Notes

Reaction equation

HRID 288401 reaction equation
[Br:21][Mg:22][c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1.[O:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1.[c:1]1([C:7]2=[CH:12][CH2:11][N:10]([CH2:13][CH:14]3[CH2:15][C:16](=[O:20])[CH2:17][CH2:18][CH2:19]3)[CH2:9][CH2:8]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([C:7]2=[CH:12][CH2:11][N:10]([CH2:13][CH:14]3[CH2:15][C:16]([c:23]4[cH:24][cH:25][cH:26][cH:27][cH:28]4)=[CH:17][CH2:18][CH2:19]3)[CH2:9][CH2:8]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 117778783-[(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)methyl]cyclohexanoneHCID 178418255HCID 178418255, compound

Product 1

HCID 104492741-[(3-Phenyl-3-cyclohexenyl)methyl]-4-phenyl-1,2,3,6-tetrahydropyridine

Sources & evidence

ORD record
ord-26037a8c611b4984933937ded1e9e800
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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