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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 28841Generated: October 29, 2026

tert-butyl{(3R)-1-[(1-hydroxycyclohexyl)(2-naphthyl)acetyl]pyrrolidin-3-yl}carbamate → HCID 68854062, compound

https://huagongshe.com/reaction/28841

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl{(3R)-1-[(1-hydroxycyclohexyl)(2-naphthyl)acetyl]pyrrolidin-3-yl}carbamateHCID 86599049—
ReactantHCID 86600423HCID 86600423—
ProductHCID 68854062HCID 68854062—

Reaction Steps

In an analogous manner to Example 1, step 2, 1-[2-[(3R)-3-aminopyrrolidin-1-yl]-1-(2-naphthyl)ethylcyclohexanol dihydrochloride was prepared from tert-butyl {(3R)-1-[(1-hydroxycyclohexyl)(2-naphthyl)acetyl]pyrrolidin-3-yl}carbamate. MS (ESI) m/z 339; HRMS: calcd for C22H30N2O+H+, 339.24309; found (ESI, [M+H]+), 339.243.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07419980B2
Source datasetuspto-grants-2008_09
ORD IDord-fdd39cd513c047619cf99a7e0873ef74
Source noteuspto-grants-2008_09