Piperazine → 2-(Piperazin-1-yl)-6-(trifluoromethyl)benzonitrile
Reaction equation
[CH2:14]1[CH2:15][NH:16][CH2:17][CH2:18][NH:19]1.[F:1][c:2]1[c:3]([C:4]#[N:5])[c:6]([C:10]([F:11])([F:12])[F:13])[cH:7][cH:8][cH:9]1.[O:20]1[CH2:21][CH2:22][O:23][CH2:24][CH2:25]1>>[c:2]1([N:16]2[CH2:15][CH2:14][NH:19][CH2:18][CH2:17]2)[c:3]([C:4]#[N:5])[c:6]([C:10]([F:11])([F:12])[F:13])[cH:7][cH:8][cH:9]1Participants
4
Sources & evidence
- ORD record
- ord-16949d602ac449408ec188b9df845627
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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