Water → 4-{2-(2,4-dichlorophenyl)-5-methyl-4-[(piperidin-1-ylamino)carbonyl]-1H-imidazol-1-yl}phenyl 5-chlorothiophene-2-sulfonate

HRID 288519Notes

Reaction equation

HRID 288519 reaction equation
[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[Cl:1][c:2]1[c:3](-[c:9]2[n:10](-[c:24]3[cH:25][cH:26][c:27]([OH:30])[cH:28][cH:29]3)[c:11]([CH3:23])[c:12]([C:14](=[O:15])[NH:16][N:17]3[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22]3)[n:13]2)[cH:4][cH:5][c:6]([Cl:8])[cH:7]1.[Cl:38][c:39]1[cH:40][cH:41][c:42]([S:44](=[O:45])(=[O:46])[Cl:47])[s:43]1.[Cl:49][CH2:50][Cl:51].[OH2:48]>>[Cl:1][c:2]1[c:3](-[c:9]2[n:10](-[c:24]3[cH:25][cH:26][c:27]([O:30][S:44]([c:42]4[cH:41][cH:40][c:39]([Cl:38])[s:43]4)(=[O:45])=[O:46])[cH:28][cH:29]3)[c:11]([CH3:23])[c:12]([C:14](=[O:15])[NH:16][N:17]3[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22]3)[n:13]2)[cH:4][cH:5][c:6]([Cl:8])[cH:7]1

Participants

6

Reactant 5

HCID 962WaterHCID 6344DichloromethaneHCID 8471TriethylamineHCID 27339255-Chlorothiophene-2-sulfonyl chlorideHCID 589650752-(2,4-Dichlorophenyl)-1-(4-hydroxyphenyl)-5-methyl-1H-imidazole-4-carboxylic acid piperidin-1-ylamide

Product 1

HCID 166667184-{2-(2,4-dichlorophenyl)-5-methyl-4-[(piperidin-1-ylamino)carbonyl]-1H-imidazol-1-yl}phenyl 5-chlorothiophene-2-sulfonate

Sources & evidence

ORD record
ord-a762492162674b7b9f9804487f7b9d62
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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