反应详情

5 cm3 of ethylbenzene and 2.6 g of aluminum chloride are mixed with magnetic stirring in a 50-cm3 flask. The solution is cooled in an ice bath and 1 g of succinic anhydride is then added. The reaction mixture is stirred for 1 h 30 min at a temperature of 0° C. and then for 3 h at room temperature. It is poured into ice. The resulting mixture is acidified by adding 1N hydrochloric acid (pH 3-4). It is extracted with 3 volumes of ether. The organic phases are washed 3 times with 10% potassium carbonate solution. The aqueous phases are combined and acidified by adding concentrated hydrochloric acid. The precipitate obtained is drained and then recrystallized.

1. temperatureThe solution is cooled in an ice bath
2. stirringThe reaction mixture is stirred for 1 h 30 min at a temperature of 0° C.
3. additionIt is poured into ice
4. extractionIt is extracted with 3 volumes of ether
5. washThe organic phases are washed 3 times with 10% potassium carbonate solution
6. additionby adding concentrated hydrochloric acid
7. customThe precipitate obtained
8. customrecrystallized