HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Cyanide → 4-(7-Methoxy-1-naphthyl)butyronitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Cyanide | HCID 9032 | — |
| Reactant | 3-(7-Methoxy-1-naphthyl)propyl mesylate | HCID 15336867 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 4-(7-Methoxy-1-naphthyl)butyronitrile | HCID 15336868 | — |
Reaction Steps
In a 100-cm3 flask, the 3-(7-methoxy-1-naphthyl)propyl mesylate obtained in stage D is dissolved in DMSO. KCN is added and the mixture is brought to reflux for 2 h. It is allowed to cool. It is poured into a water/ice mixture. The resulting mixture is extracted with ether. The organic phase is washed with water, dried over CaCl2 and evaporated. The product obtained is recrystallized.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05731352 |
| Source dataset | uspto-grants-1998_03 |
| ORD ID | ord-ebf01e6b38bc42c089b9940d05b2423f |
| Source note | uspto-grants-1998_03 |