Hydrochloric Acid → N-([1,3]thiazolo[5,4-b]pyridin-2-yl)spiro[1-azabicyclo[2.2.1]heptane-3,5'-4H-1,3-oxazole]-2'-amine

HRID 288803Notes

Reaction equation

HRID 288803 reaction equation
[ClH:16].[ClH:17].[NH2:18][CH2:19][C:20]1([OH:27])[CH2:21][N:22]2[CH2:23][CH2:24][CH:25]1[CH2:26]2.[n:1]1[c:2]([N:10]=[C:11]([S:12][CH3:13])[S:14][CH3:15])[s:3][c:4]2[n:5][cH:6][cH:7][cH:8][c:9]12>>[n:1]1[c:2]([NH:10][C:11]2=[N:18][CH2:19][C:20]3([CH2:21][N:22]4[CH2:23][CH2:24][CH:25]3[CH2:26]4)[O:27]2)[s:3][c:4]2[n:5][cH:6][cH:7][cH:8][c:9]12

Participants

4

Reactant 3

HCID 313Hydrochloric Acid2×HCID 147899993-(Aminomethyl)-1-azabicyclo[2.2.1]heptan-3-olHCID 58088154Dimethyl thiazolo[5,4-b]pyridin-2-ylcarbonimidodithioate

Product 1

HCID 75965056N-([1,3]thiazolo[5,4-b]pyridin-2-yl)spiro[1-azabicyclo[2.2.1]heptane-3,5'-4H-1,3-oxazole]-2'-amine

Sources & evidence

ORD record
ord-d183100ecdb34906a499c3d463118010
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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