Propargyl alcohol → 3-(4-Fluorophenyl)prop-2-yn-1-ol

HRID 288835Notes

Reaction equation

HRID 288835 reaction equation
[CH2:9]([C:10]#[CH:11])[OH:12].[CH:13]([NH:14][CH:15]([CH3:16])[CH3:17])([CH3:18])[CH3:19].[Cu:20][I:21].[F:1][c:2]1[cH:3][cH:4][c:5]([I:8])[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([C:11]#[C:10][CH2:9][OH:12])[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 7859Propargyl alcoholHCID 7912DiisopropylamineHCID 96054-FluoroiodobenzeneHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

Product 1

HCID 27826983-(4-Fluorophenyl)prop-2-yn-1-ol

Sources & evidence

ORD record
ord-1009bf6c132d4dc8a6540976c6b4171b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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