HRID28899

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID31268

Pyrrolidine

C4H9N

结构：CN(C)C(=O)Nc1ccc(-c2n[nH]cc2-c2ccnc3[nH]c(-c4ccc(C=O)cc4)cc23)cc1

HCID178484687

未命名化合物

PRODUCTS

生成物

结构：CN(C)C(=O)Nc1ccc(-c2n[nH]cc2-c2ccnc3[nH]c(-c4ccc(CN5CCCC5)cc4)cc23)cc1

HCID178484686

未命名化合物

PROCEDURE

实验过程

Following the procedure described for Intermediate 101 using N′-(4-{4-[2-(4-formylphenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-1H-pyrazol-3-yl}phenyl)-N,N-dimethylurea and pyrrolidine provided the title compound. ESMS [M+H]+: 506.4

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-0539bbe2b85a43f186bc7a1656771d83
来源数据集: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07419988B2
来源说明: uspto-grants-2008_09

反应 SMILES

[CH:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[NH:34][C:12]3=[N:13][CH:14]=[CH:15][C:16]([C:17]4[C:18]([C:22]5[CH:27]=[CH:26][C:25]([NH:28][C:29](=[O:33])[N:30]([CH3:32])[CH3:31])=[CH:24][CH:23]=5)=[N:19][NH:20][CH:21]=4)=[C:11]3[CH:10]=2)=[CH:5][CH:4]=1)=O.[NH:35]1[CH2:39][CH2:38][CH2:37][CH2:36]1>>[CH3:32][N:30]([CH3:31])[C:29]([NH:28][C:25]1[CH:26]=[CH:27][C:22]([C:18]2[C:17]([C:16]3[CH:15]=[CH:14][N:13]=[C:12]4[NH:34][C:9]([C:6]5[CH:5]=[CH:4][C:3]([CH2:1][N:35]6[CH2:39][CH2:38][CH2:37][CH2:36]6)=[CH:8][CH:7]=5)=[CH:10][C:11]=34)=[CH:21][NH:20][N:19]=2)=[CH:23][CH:24]=1)=[O:33]