Dichloromethane → HCID 86598508, compound

HRID 289052Notes

Reaction equation

[CH3:40][S:41]([Cl:42])(=[O:43])=[O:44].[CH3:45][CH2:46][N:47]([CH2:48][CH3:49])[CH2:50][CH3:51].[Cl:52][CH2:53][Cl:54].[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH2:9][C:10](=[O:11])[NH:12][CH:13]2[c:14]3[cH:15][n:16][c:17]([CH2:23][CH2:24][OH:25])[n:18][c:19]3[CH2:20][CH2:21][CH2:22]2)[NH:26][S:27](=[O:28])(=[O:29])[c:30]2[cH:31][c:32]([C:36]([F:37])([F:38])[F:39])[cH:33][cH:34][cH:35]2)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH2:9][C:10](=[O:11])[NH:12][CH:13]2[c:14]3[cH:15][n:16][c:17]([CH2:23][CH2:24][O:25][S:41]([CH3:40])(=[O:43])=[O:44])[n:18][c:19]3[CH2:20][CH2:21][CH2:22]2)[NH:26][S:27](=[O:28])(=[O:29])[c:30]2[cH:31][c:32]([C:36]([F:37])([F:38])[F:39])[cH:33][cH:34][cH:35]2)[cH:6][cH:7]1

Participants

Reactant 4

HCID 6344Dichloromethane

HCID 8471Triethylamine

HCID 31297Methanesulfonyl chloride

HCID 689308143-(4-fluorophenyl)-N-[2-(2-hydroxy-ethyl)-5,6,7,8-tetrahydro-quinazolin-5-yl]-3-(3-trifluoromethyl-benzenesulfonylamino)-propionamide

Product 1

HCID 86598508HCID 86598508, compound

Sources & evidence

ORD record: ord-1478133df6e34f0aa9e0f0e3d359805d
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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