Dimethylformamide → (R)-tert-Butyl (1-(4-chlorobenzyl)pyrrolidin-3-yl)carbamate

HRID 289169Notes

Reaction equation

HRID 289169 reaction equation
[C:10]([CH3:11])([CH3:12])([CH3:13])[O:14][C:15](=[O:16])[NH:17][CH:18]1[CH2:19][NH:20][CH2:21][CH2:22]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][Cl:7])[cH:8][cH:9]1.[O:23]=[CH:24][N:25]([CH3:26])[CH3:27]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][N:20]2[CH2:19][CH:18]([NH:17][C:15]([O:14][C:10]([CH3:11])([CH3:12])[CH3:13])=[O:16])[CH2:22][CH2:21]2)[cH:8][cH:9]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 77231-Chloro-4-(chloromethyl)benzeneHCID 2757234tert-butyl N-(pyrrolidin-3-yl)carbamate

Product 1

HCID 18426224(R)-tert-Butyl (1-(4-chlorobenzyl)pyrrolidin-3-yl)carbamate

Sources & evidence

ORD record
ord-b3e6af14ae2b48a49345fd6432e9172a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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