Tetrahydrofuran → 4-{4-[3-(4-Benzyloxy-pyrimidin-2-yloxy)-propyl]-piperazin-1-yl}-2-tert-butyl-6-cyclopropyl-pyrimidine
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[n:6][c:7]([CH:21]2[CH2:22][CH2:23]2)[cH:8][c:9]([N:11]2[CH2:12][CH2:13][N:14]([CH2:17][CH2:18][CH2:19][OH:20])[CH2:15][CH2:16]2)[n:10]1.[CH2:24]([Li:25])[CH2:26][CH2:27][CH3:28].[CH2:29]([c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1)[O:36][c:37]1[n:38][c:39]([S:43]([CH3:44])(=[O:45])=[O:46])[n:40][cH:41][cH:42]1.[O:47]1[CH2:48][CH2:49][CH2:50][CH2:51]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[n:6][c:7]([CH:21]2[CH2:22][CH2:23]2)[cH:8][c:9]([N:11]2[CH2:12][CH2:13][N:14]([CH2:17][CH2:18][CH2:19][O:20][c:39]3[n:38][c:37]([O:36][CH2:29][c:30]4[cH:31][cH:32][cH:33][cH:34][cH:35]4)[cH:42][cH:41][n:40]3)[CH2:15][CH2:16]2)[n:10]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-ee30e5213111473cb5fae2c13f02694a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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