Hydrochloric Acid → 1-(5-Bromopyridin-3-YL)-2,2,2-trifluoroethan-1-amine

HRID 289314Notes

Reaction equation

HRID 289314 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH:8]([C:9]([F:10])([F:11])[F:12])[NH:13][S:14]([C:15]([CH3:16])([CH3:17])[CH3:18])=[O:19])[cH:5][n:6][cH:7]1.[CH3:27][OH:28].[ClH:20].[O:21]1[CH2:22][CH2:23][O:24][CH2:25][CH2:26]1>>[Br:1][c:2]1[cH:3][c:4]([CH:8]([C:9]([F:10])([F:11])[F:12])[NH2:13])[cH:5][n:6][cH:7]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 312751,4-DioxaneHCID 59578414N-(1-(5-bromopyridin-3-yl)-2,2,2-trifluoroethyl)-2-methylpropane-2-sulfinamide

Product 1

HCID 595784171-(5-Bromopyridin-3-YL)-2,2,2-trifluoroethan-1-amine

Sources & evidence

ORD record
ord-fd9f330de3a54add9cea70d120c7f63e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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